Robert Crumb

You must thank the gods for art, those of us who have been fortunate enough to stumble onto this means of venting our craziness, our meanness, our towering disgust.
-R. Crumb

What we kids didn't understand was that we were living in a commercial, commodity culture. Everything in our environment had been bought and sold. As middle class Americans, we basically grew up on a movie set. The conscious values that are pushed are only part of the picture. The medium itself plays a much bigger part than anyone realizes: the creation of illusion. We are living surrounded by illusion, by professionally created fairy tales. We barely have contact with the real world.
-The R. Crumb Handbook by Robert Crumb and Peter Poplaski

The fine art world and the commercial art industry are both all about money. It's hard to say which is more contemptible: the fine art world with its double talk and pretensions to the cultural high ground, or the world of commercial art trying to sell to the largest mass market it can reach. A serious artist really shouldn't be too deeply involved in either of these worlds. It's best to be on the fringe of them. In general, if you want to be a success and make the money, you have to play the game. It's no different in the fine art world, it's just a slightly different game. Essentially, you're marketing an illusion. It's much easier to lie to humans and trick them than to tell them the truth. They'd much rather be bamboozled than be told the truth, because the way to trick them is to flatter them and tell them what they want to hear, to reinforce their existing illusions. They don't want to know the truth. Truth is a bring-down, a bummer, or it's just too complicated, too much mental work to grasp.
-The R. Crumb Handbook by Robert Crumb and Peter Poplaski

I took some bad acid in November of 1965, and the after effect left me crazy and helpless for six months. My mind would drift into a place that was very electrical and crackly, filled with harsh, abrasive, low grade, cartoony, tawdry carnival visions. There was a nightmarish mechanical aspect to everyday life. My ego was so shattered, so fragmented that it didn't get in the way during what was the most unself-conscious period of my life. I was kind of on automatic pilot and was still constantly drawing. Most of my popular characters—Mr. Natural, Flaky Foont, Angelfood McSpade, Eggs Ackley, The Snoid, The Vulture Demonesses, Av' n' Gar, Shuman the Human, the Truckin' guys, Devil Girl—all suddenly appeared in the drawings in my sketchbook in this period, early 1966. Amazing! I was relieved when it was finally over, but I also immediately missed the egoless state of that strange interlude. LSD put me somewhere else. I wasn't sure where. All I know is, it was a strange place. Psychedelic drugs broke me out of my social programming. It was a good thing for me, traumatic though, and I may have been permanently damaged by the whole thing, I'm not sure. I see LSD as a positive, important life experience for me, but I certainly wouldn't recommend it to anyone else.
-The R. Crumb Handbook by Robert Crumb and Peter Poplaski

I was taking LSD periodically, every couple of months. I was in a strange state of mind, influenced by these visions. ... I was trying to draw it in my sketchbook, and that began to coalesce into these comic strips that were stylistically based on grotesque, vulgar humor comics of the thirties and forties. ... All of those characters came out of that crazy visionary period that I couldn’t shut off. It was spontaneous, but I was so crazy, I was really out of my mind, it was like schizophrenia. It was like what produces art by crazy people in a madhouse. Anything could be an influence, anything I heard. I was in Chicago in early ’66 and the radio was on, there was some tune playing, it was a black station, and this announcer said, That was Mr. Natural. I just started drawing Mr. Natural, this bearded guru-type character in my sketchbook, it just came out.
"R. Crumb, The Art of Comics No. 1", The Paris Review, Summer 2010, No. 193

source