https://scitechdaily.com/eat-more-weigh-less-why-whole-foods-are-the-real-weight-loss-hack/
A
clinical trial in the UK found that overweight adults lost twice as
much weight on a minimally processed diet compared to an ultraprocessed
one, even when both met official nutritional guidelines.
The 16-week randomized study, published in Nature Medicine, gave participants either home-style meals like spaghetti Bolognese or packaged foods such as protein bars and prepared lasagna. “This new study shows that even when an ultraprocessed diet meets nutritional guidelines, people will still lose more weight eating a minimally processed diet,” coauthor Dr. Kevin Hall told CNN.
Participants on the minimally processed diet consumed 290 fewer calories per day and lost about 2% of their body weight in eight weeks, while those on the ultraprocessed diet ate 120 fewer calories and lost less. LDL cholesterol dropped more in the ultraprocessed group, a result researchers say needs further investigation. Editorial author Marion Nestle noted that taste may have influenced intake: “They deemed the minimally processed diet less tasty.”
Researchers observed reductions in triglycerides and body fat, but limited change in broader cardiovascular markers. Less than 1% of UK adults follow full dietary guidance, while in the U.S., nearly 60% of adult calories come from ultraprocessed foods. Experts say nutrient quality matters more than the processing level itself and urge consumers to focus on fiber, sugar, salt, and additive content.
The 16-week randomized study, published in Nature Medicine, gave participants either home-style meals like spaghetti Bolognese or packaged foods such as protein bars and prepared lasagna. “This new study shows that even when an ultraprocessed diet meets nutritional guidelines, people will still lose more weight eating a minimally processed diet,” coauthor Dr. Kevin Hall told CNN.
Participants on the minimally processed diet consumed 290 fewer calories per day and lost about 2% of their body weight in eight weeks, while those on the ultraprocessed diet ate 120 fewer calories and lost less. LDL cholesterol dropped more in the ultraprocessed group, a result researchers say needs further investigation. Editorial author Marion Nestle noted that taste may have influenced intake: “They deemed the minimally processed diet less tasty.”
Researchers observed reductions in triglycerides and body fat, but limited change in broader cardiovascular markers. Less than 1% of UK adults follow full dietary guidance, while in the U.S., nearly 60% of adult calories come from ultraprocessed foods. Experts say nutrient quality matters more than the processing level itself and urge consumers to focus on fiber, sugar, salt, and additive content.

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